Progesterone(P4)
hormoneDefinition
A hormone produced primarily by the corpus luteum after ovulation that prepares the uterine lining for embryo implantation.
In IVF Treatment
After embryo transfer, progesterone supplementation is essential to support the uterine lining. It is given as injections (PIO), vaginal suppositories (Endometrin, Crinone), or oral capsules and continued until 8-12 weeks of pregnancy.
Frequently Asked Questions
How long do I take progesterone after transfer?
Most clinics continue progesterone supplementation until 8-12 weeks gestation, when the placenta takes over production. Stopping too early increases the risk of miscarriage.
What is a good progesterone level after transfer?
For PIO, levels above 20 ng/mL are generally considered adequate. For vaginal progesterone, serum levels are lower but local uterine levels are sufficient. Your clinic will monitor and adjust.